What are CB1 and CB2 Receptors? (and how Does CBD Work With Them?)

by Remedy Staff | Jun 22, 2020

CB1 and CB2 Receptors

“…The endocannabinoid system’s most important function is to maintain homeostasis. It does this by leveraging endocannabinoids and CB1 and CB2 cannabinoid receptors in the central and peripheral nervous systems and the immune system. When the body detects an imbalance with a process regulated by the ECS, it produces cannabinoids that interact with receptors. This generates a chemical process that targets and resolves the imbalance and returns the body to a state of homeostasis, or perfect balance.  As you can see, CB1 and CB2 receptors are incredible structures. One of their most amazing jobs is determining how endocannabinoids AEA and 2-AG interact within the body.  AEA, or anandamide, is an endocannabinoid that is similar in structure to THC. A powerful neurotransmitter, AEA gets its name from the Sanskrit word Ananda, which means “happiness” or “bliss.” As you may imagine, AEA is credited with producing euphoria. While scientists are still studying AEA and all endocannabinoids and their impact on our physiology, we know anandamide regulates processes like memory, pain, body temperature, motivation, and fertility. Amazingly enough, AEA also increases neurogenesis, thus reducing anxiety and inflammation.  2-AG, meanwhile, is a single member of a larger group of molecules that come from arachidonic acid. Arachidonic acid is a type of fatty acid that plays a role in cellular signaling and acts as a key inflammatory intermediate as well as a vasodilator, or blood vessel widener…”

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